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Alzheimer's & Sleep Apnea: The Startling Connections with Poor Sleep

Christopher Garvey Sleep Consultant and COO

Christopher Garvey

Meet Christopher Garvey, our professional sleep consultant! He's the lead writer for The Good Night Blog, where his tips and tricks help people sleep better and feel great. Christopher's insider knowledge and expertise are second to none, and his work is reviewed by our Medical Advisory Board to ensure that all advice is medically sound. With Christopher on your side, you can say goodbye to counting sheep and hello to sweet dreams!

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What is Alzheimer's Disease?

Alzheimer's disease is a debilitating and devastating form of dementia that affects millions of people around the world. This progressive brain disorder causes problems with memory, thinking, and behavior, and can ultimately lead to a complete loss of cognitive and physical function.

One of the most challenging aspects of Alzheimer's is that it often develops slowly and can go undiagnosed for many years. However, as the disease progresses, it becomes increasingly difficult for individuals to carry out even the simplest of tasks, such as getting dressed or preparing a meal.

While the exact causes of Alzheimer's are not yet fully understood, research suggests that a combination of genetic, lifestyle, and environmental factors may play a role in its development. There is currently no cure for Alzheimer's, but there are a range of treatments and interventions available that can help to manage symptoms and improve quality of life for those affected.

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How Alzheimer's Disease Relates to Sleep:

Poor sleep has long been linked to various health issues, and recent studies have shown a strong correlation between poor sleep and Alzheimer's disease. Here are some of the key connections between the two:

Beta-amyloid buildup: Beta-amyloid is a protein that accumulates in the brains of people with Alzheimer's disease, leading to the formation of plaques that disrupt brain function. Studies have shown that poor sleep can increase beta-amyloid buildup, potentially increasing the risk of Alzheimer's disease.

Neurodegeneration: Neurodegeneration is the progressive loss of neurons in the brain, and it is a hallmark of Alzheimer's disease. Poor sleep has been linked to neurodegeneration, and studies have shown that people who get less sleep have more brain shrinkage than those who sleep well.

Memory impairment: Memory impairment is a common symptom of Alzheimer's disease, and poor sleep has been shown to impair memory consolidation, making it more difficult for the brain to form new memories.

Inflammation: Inflammation is a natural immune response to injury or infection, but chronic inflammation has been linked to a number of health problems, including Alzheimer's disease. Poor sleep has been shown to increase inflammation in the body, potentially contributing to the development of Alzheimer's disease.

Sleep apnea: Sleep apnea is a sleep disorder characterized by pauses in breathing during sleep, and it has been linked to an increased risk of Alzheimer's disease. Sleep apnea can cause intermittent hypoxia, or a lack of oxygen, which has been shown to increase beta-amyloid production.

Circadian rhythm disruption: The circadian rhythm is the body's internal clock that regulates sleep and wake cycles, and disruption of the circadian rhythm has been linked to an increased risk of Alzheimer's disease. Poor sleep can disrupt the circadian rhythm, potentially contributing to the development of Alzheimer's disease.

Insulin resistance: Insulin resistance is a condition in which the body's cells become resistant to the effects of insulin, leading to high blood sugar levels. Insulin resistance has been linked to an increased risk of Alzheimer's disease, and poor sleep has been shown to increase insulin resistance in the body.

Hormonal changes: Hormonal changes can also be a factor in the relationship between poor sleep and Alzheimer's disease. Studies have shown that poor sleep can alter the levels of hormones such as cortisol and melatonin, which are involved in the regulation of inflammation and the circadian rhythm, respectively.

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How Sleep Apnea Impacts Alzheimer's Disease:

Did you know that recent studies have found a potential link between sleep apnea and Alzheimer's disease?

According to research, there appears to be a correlation between the two conditions. Sleep apnea, which is characterized by repeated interruptions in breathing during sleep, can cause a decrease in oxygen levels and an increase in carbon dioxide levels in the body. This, in turn, can lead to inflammation and damage to brain cells, which is a hallmark of Alzheimer's disease.

In fact, a study published in the Journal of Alzheimer's Disease found that people with sleep apnea were more likely to have biomarkers for Alzheimer's disease in their cerebrospinal fluid, indicating that they may be at a higher risk for developing the disease.

Another study, published in the American Journal of Respiratory and Critical Care Medicine, found that people with sleep apnea had a greater buildup of beta-amyloid plaques in their brains. These plaques are also a hallmark of Alzheimer's disease and are thought to be one of the main causes of the condition.

While more research is needed to fully understand the relationship between sleep apnea and Alzheimer's disease, these studies suggest that treating sleep apnea may be an important step in reducing the risk of developing Alzheimer's disease.

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Improve Sleep and Reduce the Likelihood of Alzheimer's Disease:

  1. Stick to a sleep schedule: Try to go to bed and wake up at the same time every day, even on weekends. This will help regulate your body's internal clock and make it easier to fall asleep and wake up. Our free sleep tracker is a great way to start tracking your sleep schedule. Find our free download and sleep tracker guide here. It's easy to use!
  2. Create a relaxing bedtime routine: Develop a routine that helps you wind down and relax before bed. This might include taking a warm bath, reading a book, or listening to soothing music. It may be time to consider purchasing a humidifier.
  3. Limit your exposure to screens: The blue light emitted by screens can disrupt your sleep. Try to avoid using electronic devices for at least an hour before bedtime.
  4. Make your bedroom comfortable: Create a sleep-friendly environment by keeping your bedroom cool, dark, and quiet. Invest in comfortable bedding and pillows that support your sleeping posture. Find our sleep expert's picks for best sleep products on Amazon in 2023 here.
  5. Avoid caffeine, nicotine, and alcohol: These substances can interfere with your sleep. Try to avoid consuming them for several hours before bedtime.
  6. Exercise regularly: Regular exercise can help you sleep better, but avoid exercising too close to bedtime, as it can make it harder to fall asleep.
  7. Manage stress: Stress can keep you up at night. Try relaxation techniques like meditation or deep breathing exercises to help you manage stress and anxiety.
  8. Purchase an anti-snore device: SnoreLessNow is bringing Europe's #1 Mandibular Advancement Device to the US to combat snoring! With hundreds of thousands of units sold in Europe since 2005, you don't want to miss out! Subscribe your email for product discounts upon release below:


In conclusion, poor sleep has been shown to have a number of connections to Alzheimer's disease, from increasing beta-amyloid buildup and neurodegeneration to impairing memory consolidation and disrupting the circadian rhythm. It is clear that getting enough quality sleep is essential for maintaining brain health and reducing the risk of Alzheimer's disease. You can find related blog posts on sleep health below.

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